Job Details
**Senior Research Associate, Gene Delivery Process and Analytical Development - Cell Therapy**
CAROUSEL_PARAGRAPH
* Seattle, Washington
* Drug Dev and Preclinical Studies
* R1552622
* Full Time
* 01/21/2022
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At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMSs continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.
We are seeking an enthusiastic, self-driven individual to join the Gene-Deliver Process and Analytical Development team. Our team develops the end-to-end processes and technologies to deliver the critical gene-editing raw materials used in the manufacturing of engineered T cells, including viral vectors. The primary focus of this Senior Research Associate is to support process development, production, and characterization of viral vectors (e.g., lentivirus and adeno-associated virus). This team member will support current portfolio vector development programs (both upstream and downstream) and innovate on our process platforms for viral vector manufacturing.
*Responsibilities:*
* Perform hands-on experimental work in the early-phase development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production
* Support process and technology development for viral vector manufacturing platforms utilizing suspension cell culture, purification, and single-use systems.
* Design, plan, execute, and analyze lab experiments using statistical design of experiment (DoE) principles
* Maintain proper documentation of experimental results using an electronic lab notebook
* Summarize and present scientific data; communicate progress to the group, department and cross-functional project teams
* Author technical documents including protocols and internal development reports
* Maintain a safe work environment in accordance with policies/procedures/regulations.
*Education:*
* BS or MS in Biological or Chemical Engineering, Virology, Molecular or Cellular Biology, Biochemistry, or related discipline
*Qualifications:*
* 0-2 (MS) or 2+ (BS) years laboratory experience, preferably in a process development setting
* Experience performing mammalian cell culture
* Familiarity with upstream process development equipment and techniques (e.g., bioreactors, normal flow filtration, UF/DF, etc.) and/or familiarity with modern chromatographic techniques (e.g., affinity, ion-exchange, multimodal, membranes, monoliths, etc.)
* Strong scientific principles and engineering fundamentals, inclined to pro-actively solve problems
* Demonstrated ability to work in teams
* Comfortable managing multiple workstreams - independently setting priorities, resolving issues, and making recommendations
* Experience with statistical software (e.g., JMP, R, Minitab, etc.) for the design and analysis of experiments (DoE)
* Ability to communicate clearly and concisely through oral presentation and technical writing
* Passion and drive for continuous learning and transforming the lives of patients
If you want to challenge yourself, accelerate your career, and give new hope to patients, theres no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.
BMSCART
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to ...@bms.com . Visitto access our complete Equal Employment Opportunity statement.
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