Principal, Computational Chemistry


Job Details

About:

A cutting-edge small molecule drug discovery focused company with a strong emphasis on oncology, immunology, and neuroscience is looking to add headcount in their Computational Chemistry team. With exceptional funding and a robust pipeline, they are committed to advancing novel therapeutics to address unmet medical needs and improve patient outcomes.

Job Description:

Seeking a highly skilled and experienced Principal Scientist, Computational Chemistry to join their dynamic team. The ideal candidate will have a proven track record in computational chemistry within the pharmaceutical or biotechnology industry, with a minimum of 8 years of relevant experience. As a key member of our research and development team, you will lead computational chemistry programs from early discovery through clinical development, collaborating closely with internal and external stakeholders to drive the progression of our pipeline.

Responsibilities:

  • Lead and manage computational chemistry programs across a variety of therapeutic areas.
  • Utilize state-of-the-art computational techniques to support drug discovery efforts, including molecular modeling, structure-based drug design, ligand-based design, and virtual screening.
  • Work closely with medicinal chemistry, biology, and other cross-functional teams to identify and optimize lead compounds with desirable pharmacological properties.
  • Lead the development and implementation of computational strategies to address key scientific questions and accelerate the advancement of drug candidates from lead identification to IND or clinical stage.
  • Provide strategic guidance and technical expertise in computational chemistry to senior management and project teams.
  • Foster collaborations with external partners, academic institutions, and contract research organizations to leverage additional expertise and resources for our programs.
  • Stay abreast of emerging trends and technologies in computational chemistry and drug discovery, actively contributing to the continuous improvement of our research capabilities.

Qualifications:

  • Ph.D. in computational chemistry, computational biology, or a related field.
  • Minimum of 8 years of industry experience in computational chemistry or a relevant scientific discipline, preferably within the pharmaceutical or biotechnology sector.
  • Strong expertise in computational techniques and software applications commonly used in drug discovery, such as molecular modeling software (e.g., Schr dinger suite, MOE, OpenEye), molecular dynamics simulations, and cheminformatics tools.
  • Proven track record of leading and delivering successful computational chemistry programs that have advanced novel drug candidates into preclinical or clinical development.
  • Excellent communication and collaboration skills, with the ability to effectively interact with cross-functional teams and external partners.
  • Demonstrated leadership and project management capabilities, with a track record of driving innovation and achieving results in a fast-paced research environment.
  • Strong problem-solving skills and a passion for drug discovery and development.


If this role isn t for you but you are keen to explore the market, let s connect or message me at: ...@x4lifesciences.com





 X4 Life Sciences

 05/17/2024

 All cities,MA