Job Details
Associate Scientist - Antibody Discovery and Screening, Fable Therapeutics
About Us:
Fable Therapeutics (Fable) is a discovery-stage biotechnology company which develops purpose-built biologics designed to overcome therapeutic index limitations and channel therapeutic response where and when it matters.
Fable is powered by state-of-the-art structure and sequence-based protein language models. Founded by leading ML scientists and veteran biotech entrepreneurs together with top-tier venture capital firms, Fable has recently initiated its internal therapeutic pipeline and has enacted a growing list of pharma research collaborations.
Backed by a 2024 $40M Series A investment co-led by Versant Ventures and DCVC, Fable is positioned to lead in the purposeful integration of biology and computation to solve complex medical challenges. Fable s aspiration is to write the next chapter of what protein-based therapeutics can do.
Description:
We are seeking a highly skilled and motivated scientist to join our expanding team and conduct antibody and biologics screening and characterization for drug discovery. In close collaboration with our machine learning team, the experiments you design and data you provide will also be used to train state-of-the-art machine learning models. Your previous hands-on experience with manual and automated laboratory assays for screening and characterization of antibodies and biologics (e.g., ELISA, AlphaLisa, TR-Fret, Biacore, Octet, fluorescence/luminescence-based, flow cytometry) is highly desired. The ideal candidate will be an enthusiastic, flexible team member, and you will have the chance to learn and collaborate with other bench scientists and with machine learning scientists (dry-lab) as part of our multi-disciplinary approach to discover and develop precision engineered drug candidates. Come work in a friendly and high-motivation atmosphere and help build our team.
This is an on-site role. Flexible working hours to promote a balance between productivity and wellness can be accommodated with manager approval.
Responsibilities:
- Conduct a variety of antibody and biologics screening and characterization assays
- Analyze and present data and conclusions to colleagues from a variety of backgrounds
- Ensure seamless access to own and others data for machine learning
- Contribute to building and establishing the Discovery Biologics laboratory capabilities
- Help teach colleagues as part of building a collaborative team
- CRO management as needed
About You:
- BSc with 4-8 years or MSc with 0-5 years
- Demonstrated relevant industry experience
- Experience with manual and automated biochemical binding assays (e.g., ELISA, AlphaLisa, TR-Fret, Biacore, Octet), cell functional/reporter assays (e.g, fluorescence and luminescence based) and cell binding (flow cytometry)
- Experience with automation and liquid handling equipment for sample preparation and assay execution is preferred
- Experience and understanding of antibody and biologics discovery and optimization workflows preferred
- Strong sense of initiative and interest in learning new technologies and addressing disease-relevant biology
- Enjoy collaborating with diverse scientists in both the wet-lab and dry-lab
- Enthusiasm for disrupting drug discovery with new approaches to data generation & curation to allow leveraging of machine learning technologies
At Fable Therapeutics, we know that our people drive our success. We are an equal opportunity employer and we value diversity and inclusion. Fable Therapeutics provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Fable Therapeutics does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law.
For accommodations during the interview process please email ...@fabletx.com