Job Details
A pioneering biotechnology company headquartered in Boston, Massachusetts whose mission is to enhance patient lives through the development of cutting-edge therapeutics targeting protein dysfunction is looking to expand. Specializing in first-in-class tRNA-based therapies, they are at the forefront of precision protein editing to address genetically defined diseases. Their innovative approach allows for the potential treatment of various diseases, regardless of the gene or mutation location, offering hope to patients with unmet medical needs.
Seeking a talented and driven Platform Discovery Scientist to join their dynamic team, you will play a crucial role in advancing their tRNA-based therapeutic platform, contributing to the development of novel treatments for a range of genetically defined diseases. This position offers an exciting opportunity to collaborate with a multidisciplinary team of scientists and researchers in a fast-paced, innovative environment.
Key Responsibilities:
- Lead the design and execution of experiments to elucidate the mechanisms of action underlying tRNA-based therapeutics, with a focus on RNA biochemistry and northern blot analysis.
- Cultivate mammalian cell lines and perform functional assays to assess the efficacy and safety of RNA-based therapeutics.
- Utilize various omics techniques, including genomics, transcriptomics, and proteomics, to characterize therapeutic candidates and gain insights into their mechanisms of action.
- Collaborate with cross-functional teams to optimize therapeutic candidates for preclinical development, leveraging your expertise in RNA biochemistry and mammalian cell culture.
- Analyze and interpret experimental data, presenting findings to internal stakeholders and contributing to scientific publications and presentations.
- Stay abreast of the latest advancements in the field of RNA therapeutics and actively contribute to the scientific community through participation in conferences and scientific meetings.
- Contribute to the development and implementation of research strategies to advance the company's therapeutic pipeline.
Qualifications:
- Ph.D. in Molecular Biology, Biochemistry, or a related field with a focus on RNA biology or nucleic acid therapeutics.
- Strong background in RNA biochemistry, with expertise in northern blot analysis and mammalian cell culture.
- Proven experience working with various omics techniques, including genomics, transcriptomics, and proteomics.
- Proficiency in molecular biology techniques, including molecular cloning, PCR, RNA isolation, and gene expression analysis.
- Experience culturing mammalian cell lines and conducting functional assays to assess RNA-based therapeutics' efficacy and safety.
- Excellent analytical and problem-solving skills, with the ability to independently troubleshoot experimental challenges.
- Strong communication skills with the ability to effectively collaborate with cross-functional teams and present complex scientific concepts to diverse audiences.
- Highly motivated with a passion for translating scientific discoveries into innovative therapeutics to address unmet medical needs.
Compensation for this position ranges from $120,000 - $140,000 + package (commensurate to experience and background).
I am an experienced recruiter in US Life Sciences with an extensive network across the drug discovery community. If this role isn t for you but you are keen to explore the market, let s connect or message me at: ...@x4lifesciences.com