Senior Scientist, Discovery Research


Job Details

Senior Scientist, Discovery Research - Needham, MA

Location: This position may be performed on a hybrid-remote schedule, with strong preference for Massachusetts/Connecticut based candidates. *

Benefits: At Invicro you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, 401k with a 4% employer match, FSA, paid sick leave, and generous paid time off (PTO) program. You can learn more about the benefits here.

Overview

The Senior Scientist functions as a study director to manage the design, execution, analysis, and reporting of pre-clinical discovery research studies across various therapeutic areas. The Senior Scientist is expected to deploy their scientific domain expertise to 1) lead communications with sponsors, 2) interface with business development teams, 3) engage laboratory staff and IACUC, and 4) coordinate with project management and data analysis teammates to manage all aspects of studies from initial pre-clinical study design to final report. This role will also include management and mentorship of junior scientists to support their growth and development within the Discovery Research team.

Essential Job Functions

  • Manage the design, execution, analysis, and reporting of pre-clinical discovery research studies whilst following Discovery Research workflows and ensuring collected and reported data is of high quality standard
  • Accountable for study delivery (from study open to completion) and all external communication with study Sponsors
  • Author and/or review technical documents including study design quotes, study protocols, final reports, presentations, and abstracts/manuscripts/white papers, etc.
  • Be the sponsor-facing Scientist with the responsibilities of updating the sponsor during protocol development, during key study milestones, and presenting the results; the Scientist is expected to represent Invicro externally in a professional manner
  • Acquire and maintain sufficient scientific knowledge on the disease of interest, its basic biology, and how the specific study fits within that field to engage in relevant discussions with sponsors
  • Responsible for communication of study requirements and timelines to both the subcontractor site/internal Lab Coordinators and to the Study Manager/Analysis Manager
  • Provide team leadership on projects as follows:
    • Guide all internal study-related communications, including study design and technical approach planning
    • Create and maintain an open and supportive internal team environment
    • Demonstrate adaptability, a logical approach to problem solving, and high standards of attention to detail
    • Support teammates in your key areas of scientific expertise
    • Maintain clear and accurate technical records
  • Delegates and oversees scientific and project management tasks when managing large programs of work
  • Manages and mentors junior scientific staff and supports career development
  • Organizes and leads external project/program level meetings
  • Manages Sponsors expectations for study timelines and study execution and addresses any delay/issues with the study/program, including escalating to Director level and above if support is needed
  • Offers advanced expertise and leadership to the analysis team, ensuring analytical approach and data presentation align with study objectives, including complex studies; gives timely feedback on updates or desired changes
  • Leads meetings with external Sponsors, including new Sponsors and novel programs, to offer scientific expertise and information on Invicro capabilities
  • Identifies and pursuing new business opportunities, partnerships, or collaborations that align with Invicro's strategic goals
  • Other duties as assigned.
Qualifications

  • PhD or MSc (with equivalent experience) in a relevant field (e.g., Biology, Biochemistry, Pharmacology, Toxicology, Engineering, Physics)
  • 6+ years applicable industry or postdoctoral experience or equivalent or scientific/technical Masters with 10+ years applicable industry experience.
  • Knowledge and experience in pre-clinical in vivo imaging (PET, SPECT, MRI, or CT) including understanding of theory and applying imaging to the study of disease in one or more therapeutic areas to study drug effects, biodistribution, and target engagement
  • Hands-on experience acquiring pre-clinical imaging data including familiarity with data acquisition, analysis techniques, quality control, and experience in interpretation and presentation of such data
  • Demonstrated leadership in a team environment and ability to interact professionally and confidentially with collaborators, customers, and/or subcontractors
  • Experience in the design, analysis, and interpretation of pharmacology and/or efficacy studies
  • Hands-on experience establishing and optimizing in vivo pharmacology models and assays
  • A working knowledge of relevant in vitro/ex vivo methodologies including radioligand binding, autoradiography, and immunohistochemistry
  • Small molecule or biologics radiochemistry
  • Management experience
  • Excellent verbal and written communication skills as well as strong analytical skills
  • An ability to organize own work, set priorities, and determine requirements so multiple tasks are achieved in a fast-paced environment
  • An ability to work effectively with vision, integrity, and flexibility
  • A teamwork orientation, with commitment to working collaboratively

What We Offer

  • Competitive salary
  • Full Benefits
  • 401k with generous matching
  • Flexible vacation policy

About Us

Headquartered in Boston, MA, Invicro was founded in 2008 with the mission of improving the role and function of imaging in translational drug discovery and development across all therapeutic areas. Today, Invicro s multi-disciplinary team provides solutions to pharmaceutical and biotech companies across all stages of the drug development pipeline (Phase 0-IV), all imaging modalities and all therapeutic areas, including neurology, oncology, and systemic and rare diseases. Invicro s quantitative biomarker services, advanced analytics and AI tools, and clinical operational services are backed by the company s industry-leading software informatics platforms, VivoQuant and iPACS , as well as their pioneering IQ-Analytics Platform, which includes AmyloidIQ, TauIQ and DaTIQ.

Invicro is an Equal Opportunity Employer. We maintain a drug-free work environment. All qualified applicants will receive consideration for employment without regard to actual or perceived race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, citizenship status, sex or gender (including pregnancy, childbirth and related medical conditions), parental status, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of physical or mental disability, protected medical condition as defined by applicable state or local law, genetic information, political affiliation or any other characteristic protected by applicable federal, state, or local laws and ordinances.

Invicro does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Invicro. Such resumes will be deemed the sole property of Invicro and will be processed accordingly.

  • This posting is intended for candidates residing in CT/MA. Company may make an exception to fulfill business requirements. Candidates outside of this area may contact the recruiter for more information.





 Invicro

 05/14/2024

 Needham Heights,MA