Biologist


Job Details

Biologist III

1 Year

Worcester, MA

About the Job

  • The Bioprocess Development and Launch Department at the Bioresearch Center in Worcester, MA is seeking a highly motivated molecular biologist to join the CHO Cell Line Development team and advance the Biologics pipeline.
  • The scientist in this position will have several responsibilities in supporting CHO biologics pipeline, including genetic characterization of cell lines and cell banks. A strong candidate will have in-depth experience with a variety of molecular biology techniques and mammalian cell culture/aseptic technique, as well as exceptional attention to detail, demonstrated skills and productivity in laboratory research, and strong writing and communication skills.

Key Responsibilities:

  • Characterize CHO cell lines using molecular biology techniques, including qPCR, ddPCR, Southern blot, and northern blot
  • Sanger sequencing analysis
  • Design of primer/probe reagents for gene copy number analysis
  • Use of gel and blot imaging instruments
  • Maintain detailed, accurate, and clear documentation of experiments and activities
  • Effectively organize and communicate research progress and planned activities through oral and written presentations
  • Collaborate with colleagues in the Cell Line Development group and across multiple functional areas of the Bioprocess Development and Launch department to advance the company Biologics Pipeline
  • Maintain a high level of productivity in the lab
  • Demonstrate scientific initiative and creative thinking to achieve project goals and contribute team performance in a climate of scientific rigor
  • Contribute to the smooth and effective operation of the CHO Cell Line Development labs through the 5S program
  • Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, and GxP compliance

Qualifications:

  • Bachelor s Degree or Master s Degree in Cell/Molecular Biology or a related field with 5 years of relevant experience; pharmaceutical industry experience is preferred
  • Expertise in molecular biology techniques, including DNA/RNA extraction and quantification, PCR-based assays, gel electrophoresis, blotting techniques and sequencing analysis
  • Hands-on experience with mammalian cell culture
  • Experience with DNA sequence manipulation software and common software packages such as Microsoft Office
  • Excellent written and interpersonal communication skills with the ability to build strong relationships with peers and cross-functional team members
  • Strong planning, multitasking, time management, and troubleshooting skills
  • Collaborative and proactive attitude with strong scientific curiosity, work ethic, and attention to detail
  • Authorization to work in the United States is required

Preferred Qualifications:

  • Experience with expression vector elements, construction, and molecular cloning
  • Experience with digital PCR assays, such as droplet digital PCR (ddPCR)
  • Proven track record in vector biology, cell line genetic characterization, and/or CHO cell line development





 Randstad Life Sciences US

 06/01/2024

 All cities,MA