Job Details
About Firefly Bio:
Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. Our state-of-the-art platform results in highly specific delivery of degraders to target tissue. Our mission is to realize the full potential of ADCs by unlocking new classes of payloads. Our company culture is built on the values of Focus, Integrity, Respect and Energy.
Position Summary:
The Scientist/Sr. Scientist, Cellular Assays will plan and execute in vitro to evaluate novel drug conjugates for applications in oncology and other areas of unmet medical need. The position is lab-facing and on-site. Title and compensation package will be based on prior experience.
Responsibilities:
Develop and perform in vitro cellular assays to evaluate novel payloads, antibodies, and drug conjugates on cell culture and ex vivo samples
Establish strong in-house capabilities to perform in vitro experiments with high throughput
Measure target expression on and in cells and tissues
Manage cell line procurement, storage, and inventory
Participate in project teams
Requirements and Experience:
B.S., M.S. or Ph.D. degree in relevant scientific discipline with appropriate work experience
Strong hands-on experience in designing and executing in vitro experiments to validate targets and treatment ideas using ADCs, mAbs, and small molecules
Experience with flow cytometry, cell culture, cell viability assays, Western blot analysis, cell-based fluorescence and chemiluminescence assays, and cell line engineering
Proven capabilities in maintenance of cell line health and longevity
Experience with handling animal and human tissues
Highly organized, diligent, and quality focused with good computer and documentation skills
Creativity and problem-solving skills paired with ability to excel in a highly collaborative environment
Excellent oral and written communication and interpersonal skills
Additional Skills:
Good utility of bioinformatic tools for target validation
Experience in IHC and/or proteomics
Benefits:
Every team member is essential in shaping Firefly Bio s culture and science and for our success. We offer competitive compensation packages including stock options and the opportunity to be part of ground-breaking research. Firefly Bio is an equal opportunity employer and will consider all applicants for employment. Firefly Bio does not discriminate based on race, sex, color, religion, age, national origin, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits.