Senior Research Associate - Theery

Duties:

Work with a multidisciplinary team of automation engineers, data scientist, software developers and clinical researchers to translate results from discovery to clinical tests.
Working independently, and collaboratively with scientists, to perform a wide range of routine and specialized laboratory instruments and techniques.
Operate and maintain basic laboratory instrumentation, liquid handling automation and LCMS instrumentation.
In collaboration with scientists, develop and optimize novel high-throughput proteomics and metabolomics sample preparation and LCMS methods.
Execute biomarker discovery, verification and validation studies to further test development.
Communicate recent experimental results and areas for optimization to an internal multidisciplinary team.
Document results of analyses and investigations in a reproducible manner and communicate insights to internal team.

Requirements:

Bachelors or Masters degree in biochemistry or analytical chemistry with 5+ years (Bachelors) or 3+ (Masters) relevant industry experience in biological sample preparation.
Significant hands-on experience in biological sample preparation for proteomics, metabolomics, DMPK or genomics. Familiarity with a variety of techniques (i.e. liquid-liquid extraction, SPE, SEC, enzymatic digestion, etc.).
Experience in liquid handling automation maintenance and method development is desired, but not required.
Proven history of executing successful experiments, meeting timelines, data analysis and communication of recent results to scientific team.
Hands-on experience with LCMS operation, maintenance and troubleshooting
Experience with multiple types of LCMS system (e.g., Thermo Orbitrap, Sciex 7500, Agilent QQQ etc.) is desired.
Hands on experience with a variety of proteomics and metabolomics data analysis software (e.g. Skyline, Proteome Discoverer, Spectronaut, Compound Discoverer, etc.).
Must work well in a small team setting, with ability to work independently and collaboratively while meeting deadlines.
Highly organized, exceptional attention to detail and strong documentation skills.
Must be able to organize work, multitask and manage time effectively.
Excellent communications and presentation skills, as well as a desire to work across functional teams.
Desire to focus on breakthroughs in an exciting, fast-paced startup environment.

Theery

05/19/2024

San Mateo,CA